rus
Nanotechnology
S.A.Senotrusova, A.I.Akhmetova, I.V.Yaminsky
SUPERRESOLUTION OF MICROLENSES IN THE PHYSICS OF LIVING SYSTEMS DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.168.176
The spatial resolution of any conventional optical microscope is limited by the diffraction of light waves on the objective aperture, with white light the best optical microscopes resolution is about 200 nm. One way to overcome this limitation is microlens microscopy. Microsphere microscopy is a type of label-free microscopy in which spherical microlenses are placed directly on or near the sample to produce high-resolution optical images. With label-free and real-time imaging, optical microlens microscopy shows great potential in medicine and biology.
SUPERRESOLUTION OF MICROLENSES IN THE PHYSICS OF LIVING SYSTEMS DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.168.176
The spatial resolution of any conventional optical microscope is limited by the diffraction of light waves on the objective aperture, with white light the best optical microscopes resolution is about 200 nm. One way to overcome this limitation is microlens microscopy. Microsphere microscopy is a type of label-free microscopy in which spherical microlenses are placed directly on or near the sample to produce high-resolution optical images. With label-free and real-time imaging, optical microlens microscopy shows great potential in medicine and biology.
Tags: bionanoscopy microlens microscopy microsphere physics of living systems scanning probe microscopy бионаноскопия микролинзовая микроскопия микросферы сканирующая зондовая микроскопия физика живых систем
A.A.Truhova, A.I.Akhmetova, I.V.Yaminsky
3D VISUALIZATION OF ERYTHROCYTES BY ATOMIC FORCE MICROSCOPY DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.180.184
Erythrocytes are one of the favorite objects of study in probe microscopy. First, they are easily accessible, do not require long and complex sample preparation, and, most importantly, they are replete with distinctive features that can be used in clinical diagnostics. When red blood cells circulate in the blood, they need to pass through narrow capillary openings much smaller than their own cross-sectional size. The elastic properties of the membrane allow it to pass through the bloodstream and deliver the necessary substances. The ratio of surface area to volume, the viscosity of the cytoplasm, and the internal deformability of membranes affect the ability of red blood cells to transform and pass through narrow spaces. Therefore, the morphological, structural and physical characteristics of blood cells are becoming increasingly important in the study of various diseases or in assessing the risk of their development.
3D VISUALIZATION OF ERYTHROCYTES BY ATOMIC FORCE MICROSCOPY DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.180.184
Erythrocytes are one of the favorite objects of study in probe microscopy. First, they are easily accessible, do not require long and complex sample preparation, and, most importantly, they are replete with distinctive features that can be used in clinical diagnostics. When red blood cells circulate in the blood, they need to pass through narrow capillary openings much smaller than their own cross-sectional size. The elastic properties of the membrane allow it to pass through the bloodstream and deliver the necessary substances. The ratio of surface area to volume, the viscosity of the cytoplasm, and the internal deformability of membranes affect the ability of red blood cells to transform and pass through narrow spaces. Therefore, the morphological, structural and physical characteristics of blood cells are becoming increasingly important in the study of various diseases or in assessing the risk of their development.
Tags: bionanoscopy erythrocytes scanning probe microscopy бионаноскопия сканирующая зондовая микроскопия эритроциты эхиноциты
D.G.Maglakelidze, A.A.Blinova, I.M.Shevchenko, M.A.Taravanov, M.A.Kolodkin, Y.A.Oblogin, D.A.Zhukovsky
SYNTHESIS AND STUDY OF THE STRUCTURE OF BIOACTIVE MAGNESIUM SILICATE NANOPARTICLES DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.186.194
This paper presents the results of a study of bioactive magnesium silicate nanoparticles. The nanoparticles themselves were obtained by chemical precipitation in an aqueous medium. The size and shape of the samples were examined on a TEM microscope. It is established that objects of detection by aggregates are detected. In turn, the aggregates consist of spherical magnesium silicate nanoparticles with sizes from 10 to 20 nm. At the next stage, with the help of neural network processing of experimental data, the synthesis of nanoparticles was optimized. Analysis of the obtained ternary surface showed that to obtain samples with the smallest aggregate size (700 nm), the synthesis parameters are: temperature – 50 °C, stirring speed – 600 rpm, precursor concentration – 0.5 mol/l. Having determined the optimal parameters for the synthesis of magnesium silicate, computer quantum chemical modeling was carried out. As a result of calculations, it was found that the energy of the configuration was E = –709.302 kcal/mol, the value of chemical hardness η = 0.191 eV, and softness – S = 2.62 eV–1. Based on the data obtained, it can be concluded that MgSiO3 has a high stability and is characterized as a relatively soft molecule. At the final stage of the work, the samples were examined on an IR spectrometer. An analysis of the IR spectrum showed the presence of characteristic absorption bands, which correspond to bond vibrations in the MgSiO3 molecule.
SYNTHESIS AND STUDY OF THE STRUCTURE OF BIOACTIVE MAGNESIUM SILICATE NANOPARTICLES DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.186.194
This paper presents the results of a study of bioactive magnesium silicate nanoparticles. The nanoparticles themselves were obtained by chemical precipitation in an aqueous medium. The size and shape of the samples were examined on a TEM microscope. It is established that objects of detection by aggregates are detected. In turn, the aggregates consist of spherical magnesium silicate nanoparticles with sizes from 10 to 20 nm. At the next stage, with the help of neural network processing of experimental data, the synthesis of nanoparticles was optimized. Analysis of the obtained ternary surface showed that to obtain samples with the smallest aggregate size (700 nm), the synthesis parameters are: temperature – 50 °C, stirring speed – 600 rpm, precursor concentration – 0.5 mol/l. Having determined the optimal parameters for the synthesis of magnesium silicate, computer quantum chemical modeling was carried out. As a result of calculations, it was found that the energy of the configuration was E = –709.302 kcal/mol, the value of chemical hardness η = 0.191 eV, and softness – S = 2.62 eV–1. Based on the data obtained, it can be concluded that MgSiO3 has a high stability and is characterized as a relatively soft molecule. At the final stage of the work, the samples were examined on an IR spectrometer. An analysis of the IR spectrum showed the presence of characteristic absorption bands, which correspond to bond vibrations in the MgSiO3 molecule.
Tags: bioactive nanoparticles magnesium silicate neural network processing of experimental data биоактивные наночастицы нейросетевая обработка экспериментальных данных силикат магния
G.E.Krichevsky, N.D.Oltarzhevskaya, M.A.Shchedrina, Y.S.Fidorovskaya
NANOMEDICINE. THE USE OF BIOSYNTHETICALLY PRODUCED METAL NANOPARTICLES IN A NEW GENERATION OF WOUND-HEALING DEPOTMATERIALS DEVELOPMENT DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.196.202
Nanotechnology, as an interdisciplinary and cross-sectoral technology, is now used worldwide in almost all fields of science and technology and in all branches of modern industry. The value of products derived from nanotechnology amounts to trillions of dollars. Nanotechnology is also being used effectively in all fields of medicine. New fields have appeared and consolidated: nanomedicine, nanotherapy, nanodiagnostics. Nanoparticles of various natures have a special place in medicine. This paper is devoted to practical use of silver nanoparticles in wound healing of purulent wounds. The effectiveness of the developed application containing silver nanoparticles and enzymes is presented.
NANOMEDICINE. THE USE OF BIOSYNTHETICALLY PRODUCED METAL NANOPARTICLES IN A NEW GENERATION OF WOUND-HEALING DEPOTMATERIALS DEVELOPMENT DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.196.202
Nanotechnology, as an interdisciplinary and cross-sectoral technology, is now used worldwide in almost all fields of science and technology and in all branches of modern industry. The value of products derived from nanotechnology amounts to trillions of dollars. Nanotechnology is also being used effectively in all fields of medicine. New fields have appeared and consolidated: nanomedicine, nanotherapy, nanodiagnostics. Nanoparticles of various natures have a special place in medicine. This paper is devoted to practical use of silver nanoparticles in wound healing of purulent wounds. The effectiveness of the developed application containing silver nanoparticles and enzymes is presented.
Nanomaterials
V.I.Lysenko
PREPARING OF SOLID CERAMICS FROM YTTRIUM OXIDE NANOPOWDER BY SPS METHOD DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.204.207
Strong fine-grained ceramics (about 1 μm) based on yttrium oxide nanopowder was prepared using spark plasma sintering (SPS) method. It has microhardness of 2.1 GPa.
PREPARING OF SOLID CERAMICS FROM YTTRIUM OXIDE NANOPOWDER BY SPS METHOD DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.204.207
Strong fine-grained ceramics (about 1 μm) based on yttrium oxide nanopowder was prepared using spark plasma sintering (SPS) method. It has microhardness of 2.1 GPa.
Tags: ceramics nanopowder spark plasma sintering yttrium oxide керамика нанопорошок оксид иттрия электроискровое спекание
Equipment for nanoindustry
V.V.Polevikov, E.O.Litvinenko
MODERN METHODS FOR MONITORING ELECTRICAL CURRENTS USING PHYSICAL VALUES SENSORS DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.220.230
Magnetic field sensors are very important for many sensor-based measurement applications. Therefore, measuring current values comes down to a choice between an AMR sensor and a Hall sensor. This paper presents the main advantages and disadvantages of each of the two types of sensors, methods for optimising their main characteristics, as well as the results achieved by Zelenograd Nanotechnology Centre in mastering and producing magnetic transducers.
MODERN METHODS FOR MONITORING ELECTRICAL CURRENTS USING PHYSICAL VALUES SENSORS DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.220.230
Magnetic field sensors are very important for many sensor-based measurement applications. Therefore, measuring current values comes down to a choice between an AMR sensor and a Hall sensor. This paper presents the main advantages and disadvantages of each of the two types of sensors, methods for optimising their main characteristics, as well as the results achieved by Zelenograd Nanotechnology Centre in mastering and producing magnetic transducers.
Tags: current sensor detectors hall sensor magnetoresistors амr датчики датчики тока магниторезисторы холл
D.S.Shakhov, V.P.Mikhailov, A.M.Bazinenkov, M.E.Zhukov
LINEAR PNEUMOHYDRAULIC DRIVE WITH ELECTRORHEOLOGICAL SPEED CONTROL DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.232.238
A linear pneumohydraulic drive with electrorheological (ER) control is considered to ensure movement speed of objects according to a given law. The high accuracy of movement speed maintaining of is ensured by the use of a starch-based liquid as a working medium, capable of almost instantly changing rheological properties under the action of an electric field. Calculations of potential distribution in the ER valve is carried out, as well as calculation of the flow velocity of the ER fluid in the throttle and pipelines. It has been experimentally established that effective adjustment of drive rod movement speed is carried out at air pressure of 0.4 atm at the inlet to the pneumatic cylinder and a volume concentration of working fluid dispersed phase of 25%.
LINEAR PNEUMOHYDRAULIC DRIVE WITH ELECTRORHEOLOGICAL SPEED CONTROL DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.232.238
A linear pneumohydraulic drive with electrorheological (ER) control is considered to ensure movement speed of objects according to a given law. The high accuracy of movement speed maintaining of is ensured by the use of a starch-based liquid as a working medium, capable of almost instantly changing rheological properties under the action of an electric field. Calculations of potential distribution in the ER valve is carried out, as well as calculation of the flow velocity of the ER fluid in the throttle and pipelines. It has been experimentally established that effective adjustment of drive rod movement speed is carried out at air pressure of 0.4 atm at the inlet to the pneumatic cylinder and a volume concentration of working fluid dispersed phase of 25%.
Tags: electrorheological fluid pneumohydraulic drive speed adjustment viscosity вязкость пневмогидравлический привод регулировка скорости перемещения электрореологическая жидкость
Nanomaterials
A.A.Churakova, E.M.Kayumova
CORROSION BEHAVIOR AND SURFACE ANALYSIS OF Ni-RICH TiNi ALLOY DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.208.219
In this article the corrosion behavior was considered and the surface analysis of Ti49.0Ni51.0 alloy samples in various structural (coarse-grained, ultrafine-grained, prepared by equal-channel angular pressing of a quenching sample, and ultrafine-grained after ECAP with preliminary aging) states in acid solutions – HCl and H2SO4. Studies have shown that corrosion damage in solutions of acids of various concentrations (1M, 3M) occurs most intensively in the coarse-grained state with an increased concentration of the acid solution. The formation of an ultrafine-grained structure reduces the corrosion rate; however, the ultrafine-grained state of the pre-aged alloy increases the corrosion rate compared to the unaged state in the sulfuric acid solution.
CORROSION BEHAVIOR AND SURFACE ANALYSIS OF Ni-RICH TiNi ALLOY DOI: https://doi.org/10.22184/1993-8578.2023.16.3-4.208.219
In this article the corrosion behavior was considered and the surface analysis of Ti49.0Ni51.0 alloy samples in various structural (coarse-grained, ultrafine-grained, prepared by equal-channel angular pressing of a quenching sample, and ultrafine-grained after ECAP with preliminary aging) states in acid solutions – HCl and H2SO4. Studies have shown that corrosion damage in solutions of acids of various concentrations (1M, 3M) occurs most intensively in the coarse-grained state with an increased concentration of the acid solution. The formation of an ultrafine-grained structure reduces the corrosion rate; however, the ultrafine-grained state of the pre-aged alloy increases the corrosion rate compared to the unaged state in the sulfuric acid solution.