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technospheramag
technospheramag
ТЕХНОСФЕРА_РИЦ
DOI: 10.22184/1993-8578.2024.17.1.50.54
A year ago, on January 25, 2023, the grand opening of the Lomonosov cluster took place [1]. During this year, we managed to build, improve and significantly improve. For Advanced Technologies Center, the year 2023 was successful in terms of achievements in scientific and technical terms. We have developed and assembled a significantly improved installation for combined scanning capillary microscopy and molecular 3D printing, developed a fast and effective solution for constructing physical experimental equipment, professional measuring and control electronics with highly advanced "brains" based on FPGAs. FemtoScan Online software remains one of the best solutions for processing 3D data in microscopy.
A year ago, on January 25, 2023, the grand opening of the Lomonosov cluster took place [1]. During this year, we managed to build, improve and significantly improve. For Advanced Technologies Center, the year 2023 was successful in terms of achievements in scientific and technical terms. We have developed and assembled a significantly improved installation for combined scanning capillary microscopy and molecular 3D printing, developed a fast and effective solution for constructing physical experimental equipment, professional measuring and control electronics with highly advanced "brains" based on FPGAs. FemtoScan Online software remains one of the best solutions for processing 3D data in microscopy.
Теги: atomic force microscopy bionanoscopy data processing scanning probe microscopy атомно-силовая микроскопия бионаноскопия обработка данных сканирующая зондовая микроскопия
INTRODUCTION
The Advanced Technologies Center has been specialising in hardware and software development and production of scanning probe microscopes for more than 30 years. During this time several models of microscopes have been created: Scan-7, Scan-8, FemtoScan, FemtoScan X, FemtoScan XI, FemtoScan X Ion. FemtoScan was the first in a world scanning probe microscope with full control of all measurement modes via the Internet. FemtoScan X features ultra-fast measurement modes at 1 MHz. FemtoScan XI integrates scanning capillary microscopy and 3D molecular printer modes. FemtoScan X Ion provides a large platform for scientific investigation of processes in living systems, combining a scanning probe microscope, 3D printer, biosensor and atomic scales.
FemtoScan X and FemtoScan X Ion
Capillary microscopy technique is gaining popularity in biomedical research: non-contact method of studying biological objects in natural environment provides a huge layer of opportunities for researchers. It has become possible to observe biological processes on living objects with a record temporal and spatial resolution: to assess the effect of cytotoxic substances on cells, on changes in environmental conditions, while it is possible to change biomechanical properties – to measure elasticity, to assess the objects rigidity, and to locally apply substances, proteins, etc. to cells.
Thus, the method offers unique opportunities for experimental biologists. At the same time, the work constantly requires an increase in scanning speed, which is significantly improved in the FemtoScan X Ion. FemtoScan X Ion combines a molecular 3D printer, a scanning capillary microscope and atomic scales, making it a multifunctional instrument for biological and biomedical research. The device can be used to visualise living systems in 3D with nanometre precision, register signals in a nerve cell, print biomacromolecules, and determine the mass of nanoparticles [2].
FemtoScan Online Software
Over the past year, the FemtoScan Online software was significantly improved [3].
Processing of 3D probe, optical and electron microscopy images makes it indispensable in any laboratory. FemtoScan Online software also allows you to control the FemtoScan scanning probe microscope, which has become a practical tool to develop the new technologies in materials science, biology, and medicine.
The uniqueness of FemtoScan Online lies in ability to quickly and accurately analyse 3D images, a large set of tools for quantitative analysis, and possibility to make video clips. Simple and clear interface, easy import and export of images in one click, ability to open more than 100 different data formats makes the software a real assistant for a modern researcher. Now FemtoScan Online Software is available in Russian, English and Chinese languages.
Krugozor high-tech equipment control system
Krugozor is a system for fast data acquisition and control of high-tech equipment and measuring scientific complexes. It includes software with graphical interface, a fast electronic system using a high-performance FPGA controlling a wide range of DACs, ADCs, frequency synthesizers, amplifiers, synchronous detectors, feedback systems, etc. The system is designed to be used as a central control core in microscopes, spectrometers, spectroscopes, spectrometers, spectroscopy, spectrometers, amplifiers, synchronous detectors, feedback systems, etc. The system is intended for use as a central control core in microscopes, spectrometers, lithographers, 3D printers, milling and turning centres, and robotics systems. Circumference routinely replaces oscilloscopes, frequency meters, oscillators, generators, meters, widely used not only in science but also in production.
CONCLUSION
The next year will certainly bring new developments, fruitful co-operation and interesting experiments. Are there any problems and pressing issues? Of course, yes! They exist in order to solve them and to move forward successfully. What problems arise in scientific and research and production activities? What bothers entrepreneurs, innovators, scientists and prevents them from moving forward effectively? In brief, it goes like this:
A single window of support for science is needed. All announcements about competitions and science support measures on one portal;
Russian Foundation for Basic Research – a trust fund, an example of effective support. Let’s give back!
FZ 44 and FZ 223 – the opposite effect. It is necessary to simplify the process of procurement of components and devices;
100 bids for one place in competition and tonnes of reports for the winner. This makes no sense, as the experts are obliged to read and evaluate the application, it is labour-intensive for both the expert and the applicant;
Customs gives the go-ahead! Imported components, consumables, and reagents should be delivered to scientists and innovators without delay.
We wrote about it in detail earlier [4]. We are working in this direction as well!
ACKNOWLEDGMENTS
FemtoScan Online software provided by Advanced Technologies Center, www.nanoscopy.ru.
We would like to thank the Moscow Department of Entrepreneurship and Innovation Development, the Moscow Innovation Cluster Foundation and Innovation Promotion Foundation (project No. 0071108) for their substantial support.
PEER REVIEW INFO
Editorial board thanks the anonymous reviewer(s) for their contribution to the peer review of this work. It is also grateful for their consent to publish papers on the journal’s website and SEL eLibrary eLIBRARY.RU.
Declaration of Competing Interest. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
The Advanced Technologies Center has been specialising in hardware and software development and production of scanning probe microscopes for more than 30 years. During this time several models of microscopes have been created: Scan-7, Scan-8, FemtoScan, FemtoScan X, FemtoScan XI, FemtoScan X Ion. FemtoScan was the first in a world scanning probe microscope with full control of all measurement modes via the Internet. FemtoScan X features ultra-fast measurement modes at 1 MHz. FemtoScan XI integrates scanning capillary microscopy and 3D molecular printer modes. FemtoScan X Ion provides a large platform for scientific investigation of processes in living systems, combining a scanning probe microscope, 3D printer, biosensor and atomic scales.
FemtoScan X and FemtoScan X Ion
Capillary microscopy technique is gaining popularity in biomedical research: non-contact method of studying biological objects in natural environment provides a huge layer of opportunities for researchers. It has become possible to observe biological processes on living objects with a record temporal and spatial resolution: to assess the effect of cytotoxic substances on cells, on changes in environmental conditions, while it is possible to change biomechanical properties – to measure elasticity, to assess the objects rigidity, and to locally apply substances, proteins, etc. to cells.
Thus, the method offers unique opportunities for experimental biologists. At the same time, the work constantly requires an increase in scanning speed, which is significantly improved in the FemtoScan X Ion. FemtoScan X Ion combines a molecular 3D printer, a scanning capillary microscope and atomic scales, making it a multifunctional instrument for biological and biomedical research. The device can be used to visualise living systems in 3D with nanometre precision, register signals in a nerve cell, print biomacromolecules, and determine the mass of nanoparticles [2].
FemtoScan Online Software
Over the past year, the FemtoScan Online software was significantly improved [3].
Processing of 3D probe, optical and electron microscopy images makes it indispensable in any laboratory. FemtoScan Online software also allows you to control the FemtoScan scanning probe microscope, which has become a practical tool to develop the new technologies in materials science, biology, and medicine.
The uniqueness of FemtoScan Online lies in ability to quickly and accurately analyse 3D images, a large set of tools for quantitative analysis, and possibility to make video clips. Simple and clear interface, easy import and export of images in one click, ability to open more than 100 different data formats makes the software a real assistant for a modern researcher. Now FemtoScan Online Software is available in Russian, English and Chinese languages.
Krugozor high-tech equipment control system
Krugozor is a system for fast data acquisition and control of high-tech equipment and measuring scientific complexes. It includes software with graphical interface, a fast electronic system using a high-performance FPGA controlling a wide range of DACs, ADCs, frequency synthesizers, amplifiers, synchronous detectors, feedback systems, etc. The system is designed to be used as a central control core in microscopes, spectrometers, spectroscopes, spectrometers, spectroscopy, spectrometers, amplifiers, synchronous detectors, feedback systems, etc. The system is intended for use as a central control core in microscopes, spectrometers, lithographers, 3D printers, milling and turning centres, and robotics systems. Circumference routinely replaces oscilloscopes, frequency meters, oscillators, generators, meters, widely used not only in science but also in production.
CONCLUSION
The next year will certainly bring new developments, fruitful co-operation and interesting experiments. Are there any problems and pressing issues? Of course, yes! They exist in order to solve them and to move forward successfully. What problems arise in scientific and research and production activities? What bothers entrepreneurs, innovators, scientists and prevents them from moving forward effectively? In brief, it goes like this:
A single window of support for science is needed. All announcements about competitions and science support measures on one portal;
Russian Foundation for Basic Research – a trust fund, an example of effective support. Let’s give back!
FZ 44 and FZ 223 – the opposite effect. It is necessary to simplify the process of procurement of components and devices;
100 bids for one place in competition and tonnes of reports for the winner. This makes no sense, as the experts are obliged to read and evaluate the application, it is labour-intensive for both the expert and the applicant;
Customs gives the go-ahead! Imported components, consumables, and reagents should be delivered to scientists and innovators without delay.
We wrote about it in detail earlier [4]. We are working in this direction as well!
ACKNOWLEDGMENTS
FemtoScan Online software provided by Advanced Technologies Center, www.nanoscopy.ru.
We would like to thank the Moscow Department of Entrepreneurship and Innovation Development, the Moscow Innovation Cluster Foundation and Innovation Promotion Foundation (project No. 0071108) for their substantial support.
PEER REVIEW INFO
Editorial board thanks the anonymous reviewer(s) for their contribution to the peer review of this work. It is also grateful for their consent to publish papers on the journal’s website and SEL eLibrary eLIBRARY.RU.
Declaration of Competing Interest. The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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