ORIGINALITY WITHOUT PRIVILEGE: COMPARATIVE ANALYSIS OF ELECTROFORMED AND STANDARD NITROCELLULOSE MEMBRANES IN MELATONIN IMMUNOASSAYS
Electrospinning enables manufacturing of polymer membranes composed of nanofibres. These membranes find application as filters, wound coatings, and tissue engineering scaffolds. They are also considered promising substrates for immunoassays. Despite the scientific community’s keen interest in the immunoassays based on electrospun membranes, a direct comparison with membranes formed through alternative technologies has not been conducted to date. In this study, we performed such a comparison and demonstrated that the detection of melatonin via enzyme-linked immunosorbent assay (ELISA) is virtually identical on the electrospun membranes and the conventional commercially available membranes.
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