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Issue #5/2024
Yu.D.Ivanov, I.D.Shumov, A.N.Ableev, A.F.Kozlov, E.E.Vazhenkova, V.S.Ziborov, A.Yu.Dolgoborodov, O.F.Petrov, S.V.Budnik, R.S.Churyukin, S.V.Novikov, A.M.Tereza, A.I.Archakov
ELECTRON ACCELERATOR FOR INACTIVATION OF HORSERADISH PEROXIDASE ENZYME
ELECTRON ACCELERATOR FOR INACTIVATION OF HORSERADISH PEROXIDASE ENZYME
DOI: https://doi.org/10.22184/1993-8578.2024.17.5.260.266
Nanotechnology manipulates objects with characteristic dimensions of less than 100 nm. In this work, molecules of horseradish peroxidase (HRP) enzyme with dimensions of the order of 5 nm are used as objects, and the device for their inactivation is an electron accelerator, which allows us to obtain electron beam with energy of 9.7 MeV. We demonstrate that upon an irradiation dose of 25 kGy, the activity of the enzyme decreased virtually to zero. The results obtained must be taken into account in the development of methods for sterilization of food and packaging materials for food and medical products.
Tags: electron accelerator enzyme inactivation horseradish peroxidase инактивация фермента пероксидаза хрена электронный ускоритель
Subscribe to the journal Nanoindustry to read the full article.
Nanotechnology manipulates objects with characteristic dimensions of less than 100 nm. In this work, molecules of horseradish peroxidase (HRP) enzyme with dimensions of the order of 5 nm are used as objects, and the device for their inactivation is an electron accelerator, which allows us to obtain electron beam with energy of 9.7 MeV. We demonstrate that upon an irradiation dose of 25 kGy, the activity of the enzyme decreased virtually to zero. The results obtained must be taken into account in the development of methods for sterilization of food and packaging materials for food and medical products.
Tags: electron accelerator enzyme inactivation horseradish peroxidase инактивация фермента пероксидаза хрена электронный ускоритель
Subscribe to the journal Nanoindustry to read the full article.
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