DOI: https://doi.org/10.22184/1993-8578.2025.18.1.40.46

Scanning capillary microscopy (SCM) has become a universal method for studying interactions in living cells and tissues. SCM finds successful application in biology and materials science in biophysical and electrochemical measurements. Initially, this type of microscopy was used mainly to record 3D morphology of cells in the natural environment, but soon the method began to develop due to the use of modified and multichannel capillaries, which made it possible to record active oxygen species near and inside the cell surface, evaluate deformation and other mechanical properties of the objects under study. Modern modifications of the SCM setup have made this method an important tool in bioanalytical, biophysical and materials science measurements. This paper presents a study of fibrosarcoma cells using the FemtoScan X Aion capillary microscope, developed on the basis of original electronics, mechanics and software systems.